CSIR-Centre for Cellular and Molecular Biology

The Centre for Cellular and Molecular Biology or CCMB is an Indian fundamental life science research establishment located in Hyderabad that operates under the aegis of the Council of Scientific and Industrial Research.
Variants of Drug Metabolizing Gene Identified 💊🔬🧬

A CCMB (CSIR-Centre for Cellular and Molecular Biology) research team studied the diversity of the cytochrome-P450-2C9 (CYP269) gene among 1488 Indians across 36 population groups representing different linguistic groups, castes and tribes. The CYP269 gene encodes for the enzyme CYP269. The team also discovered 8 new variants of the gene making a total of 11 variants of the gene across South Asia. Additionally, they found that a few Indian populations have more than 20% people with a deleterious variant of the gene.


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