Variants of Drug Metabolizing Gene Identified 💊🔬🧬
A CCMB (CSIR-Centre for Cellular and Molecular Biology) research team studied the diversity of the cytochrome-P450-2C9 (CYP269) gene among 1488 Indians across 36 population groups representing different linguistic groups, castes and tribes. The CYP269 gene encodes for the enzyme CYP269. The team also discovered 8 new variants of the gene making a total of 11 variants of the gene across South Asia. Additionally, they found that a few Indian populations have more than 20% people with a deleterious variant of the gene.