The American Chemical Society was founded in 1876 and chartered by the U.S. Congress. They are one of the world’s largest scientific organizations with more than 152,000 members in 130+ countries. Their mission is to advance the broader chemistry enterprise and its practitioners for the benefit of Earth and its people. Their vision is to improve people’s lives through the transforming power of chemistry.
Chemotherapeutic Drug Delivery using DNA-Based Nanogels 👨🔬🔬🧬
In a breakthrough, researchers reporting in ACS’ Nano Letters have designed DNA-Based Nanogels that can be used for selective drug delivery in cancerous cells. These nanogels break down only in cancerous cells releasing the chemotherapeutic drug. These nanogels work due to a repair enzyme called FEN1 that cuts certain parts of DNA. This enzyme is found in all cells however it is present in large amounts in cancerous cells. Special DNA structures were used to make these nanogels that FEN1 could recognize and cut. This technique was used to deliver chemotherapeutic drugs doxorubicin and vinorelbine to breast cancer cells and it was found that human breast cancer cells died at a higher rate than healthy breast cells which indicates that this technique can be effectively used to deliver chemotherapeutic drugs with high specificity with a reduced risk of side effects.
Octopus-Inspired Artificial Muscle Can Change Color and Shape Depending on Light 🐙💪💡
Researchers from Rutgers University have created a 3D-printed smart gel that changes shape when exposed to light. The material was inspired by a class of mollusks, cephalopods (squids, octopi, or cuttlefish to name a few), that have chromatophores on their skin that allows them to change its color and pattern.